TNF-beta Luciferase Reporter-HEK293 Cell Line

Product Code
RC1007
$3,005.00
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The TNF-beta Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the TNF-beta promoter. Tumor necrosis factor-beta (TNF-beta) one of the major proinflammatory cytokines, which is produced predominantly by mitogen-stimulated T lymphocytes and leukocytes. TNF-beta is involved in the regulation of various biological processes such as cell proliferation, differentiation and apoptosis. TNF-beta gene polymorphisms are also significantly associated with disease susceptibility and phenotype in patients with psoriatic arthritis. The TNF-beta induction by phorbol 12-myristate 13-acetate (PMA)  is shown in Figure 1. 
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SKU RC1007
Size 1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
Application

Application:

 Monitor the TNF-beta induction activity. Screen for activators or inhibitors of the TNF-beta signaling pathway. 

Culture conditions:

Cells should be grown at 37°C with 5% CO2 using DMEM medium supplemented with 10% FBS and
Storage Immediately upon receipt, store in liquid nitrogen.
Gene id TNF-BETA
Shipping Temp Ambient
Supplier Name Boster Biological Technology Ltd