TNF-beta Luciferase Reporter-HEK293 Cell Line
Product Code
RC1007
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The TNF-beta Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the TNF-beta promoter. Tumor necrosis factor-beta (TNF-beta) one of the major proinflammatory cytokines, which is produced predominantly by mitogen-stimulated T lymphocytes and leukocytes. TNF-beta is involved in the regulation of various biological processes such as cell proliferation, differentiation and apoptosis. TNF-beta gene polymorphisms are also significantly associated with disease susceptibility and phenotype in patients with psoriatic arthritis. The TNF-beta induction by phorbol 12-myristate 13-acetate (PMA)  is shown in Figure 1.ÂÂ
| SKU | RC1007 |
|---|---|
| Size | 1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO. |
| Application | Application: Monitor the TNF-beta induction activity. Screen for activators or inhibitors of the TNF-beta signaling pathway.ÂÂCulture conditions:Cells should be grown at 37°C with 5% CO2 using DMEM medium supplemented with 10% FBS and |
| Storage | Immediately upon receipt, store in liquid nitrogen. |
| Gene id | TNF-BETA |
| Shipping Temp | Ambient |
| Supplier Name | Boster Biological Technology Ltd |