TNF-alpha Luciferase Reporter-HEK293 Cell Line
Product Code
RC1005
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The TNF-alpha Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the TNF-alpha promoter. Tumor necrosis factor-alpha (TNF-alpha) is one of the major proinflammatory cytokines and can induce systemic inflammation, apoptotic cell death, sepsis and cachexia. Dysregulation of TNF-alpha induction is often involved in various human diseases including inflammatory bowel disease, cancer and Alzheimer's disease.  The TNF-alpha induction by phorbol 12-myristate 13-acetate (PMA)  is shown in Figure 1.
| SKU | RC1005 |
|---|---|
| Size | 1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO. |
| Application | Application:Monitor the TNF-alpha induction activity.Screen for activators or inhibitors of the TNF-alpha signaling pathway.ÂÂCulture conditions: Cells should be grown at 37°C with 5% CO2 using DMEM medium supplemented with 10% FBS and |
| Storage | Immediately upon receipt, store in liquid nitrogen. |
| Gene id | TNF-ALPHA |
| Shipping Temp | Ambient |
| Supplier Name | Boster Biological Technology Ltd |