TNF-alpha Luciferase Reporter-HEK293 Cell Line

Product Code
RC1005
$3,005.00
Order Support
Shipping Information
Product Updates
  • Keep up to date with product offers, resources and news

  • Sign up

The TNF-alpha Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the TNF-alpha promoter. Tumor necrosis factor-alpha (TNF-alpha) is one of the major proinflammatory cytokines and can induce systemic inflammation, apoptotic cell death, sepsis and cachexia. Dysregulation of TNF-alpha induction is often involved in various human diseases including inflammatory bowel disease, cancer and Alzheimer's disease.   The TNF-alpha induction by phorbol 12-myristate 13-acetate (PMA)  is shown in Figure 1.
More Information
SKU RC1005
Size 1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
Application

Application:

Monitor the TNF-alpha induction activity.Screen for activators or inhibitors of the TNF-alpha signaling pathway. 

Culture conditions:

 Cells should be grown at 37°C with 5% CO2 using DMEM medium supplemented with 10% FBS and
Storage Immediately upon receipt, store in liquid nitrogen.
Gene id TNF-ALPHA
Shipping Temp Ambient
Supplier Name Boster Biological Technology Ltd