TIGIT / NFAT Reporter - Jurkat Cell Line
Product Code
60538
$12,665.00
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Recombinant Jurkat cell line constitutively expressing a full length human TIGIT (Tcell Immunoreceptor with Immunoglobulin and ITIM domain; VSTM3), and a firefly luciferasegene under the control of nuclear factor of activator T cells (NFAT) response element. BothTIGIT and NFAT constructs have been stably integrated into Jurkat cells. TIGIT expression hasbeen confirmed by Western Blot, and TIGIT-specific NFAT response has been validated using aTIGIT ligand, CD155 (PVR).
| SKU | 60538 |
|---|---|
| Size | 2 vials |
| Application | This cell line is ideal for high throughput screening (HTS) to identify antagonistic monoclonal antibodies targeting either TIGIT or its ligands, such as CD155 in a cellular context. |
| Storage | Store in liquid nitrogen immediately upon receipt. |
| Species | Human |
| Cell Line | JURKAT |
| Tissue Type | Lymphoid Tissue |
| Gene synonyms | T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, VSIG9, V-set and transmembrane domain-containing protein 3, VSTM3 |
| Shipping Temp | Dry Ice |
| Supplier Name | BPS |