TIGIT / NFAT Reporter - Jurkat Cell Line

Product Code
60538
$12,665.00
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Recombinant Jurkat cell line constitutively expressing a full length human TIGIT (Tcell Immunoreceptor with Immunoglobulin and ITIM domain; VSTM3), and a firefly luciferasegene under the control of nuclear factor of activator T cells (NFAT) response element. BothTIGIT and NFAT constructs have been stably integrated into Jurkat cells. TIGIT expression hasbeen confirmed by Western Blot, and TIGIT-specific NFAT response has been validated using aTIGIT ligand, CD155 (PVR).
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SKU 60538
Size 2 vials
Application This cell line is ideal for high throughput screening (HTS) to identify antagonistic monoclonal antibodies targeting either TIGIT or its ligands, such as CD155 in a cellular context.
Storage Store in liquid nitrogen immediately upon receipt.
Species Human
Cell Line JURKAT
Tissue Type Lymphoid Tissue
Gene synonyms T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, VSIG9, V-set and transmembrane domain-containing protein 3, VSTM3
Shipping Temp Dry Ice
Supplier Name BPS