Spike (SARS-CoV-2, UK Variant) Pseudotyped Lentivirus (Luc Reporter)

Product Code
AMS.78112-2
$5,140.00
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The Spike (SARS-CoV-2, UK variant) Pseudotyped Lentivirus were produced with SARS-CoV-2 UK Variant Spike (Genbank Accession #QHD43416.1 with UK variant mutations; see below for details) as the envelope glycoproteins instead of the commonly used VSV-G. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter, therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (SARS-CoV-2, UK variant) pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 UK variant in a Biosafety Level 2 facility.
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SKU AMS.78112-2
Size 500 ul x 2
Application 1. Study the mechanism of viral transduction of SARS-CoV-2 UK variant.
2. Screening for neutralizing antibodies for SARS-CoV-2 Spike (UK variant) and ACE2.
Storage Lentiviruses are shipped with dry ice. For long term storage, it is recommended to store the virus at -80C. Avoid repeated freeze-thaw cycles. Titers can drop significantly with each freeze-thaw cycle.
Species SARS-CoV-2
Gene synonyms coronavirus, covid, covid-19, covid19, Sars-cov-2 B.1.1.7, sars cov 2, sarscov2, UK variant, UK lenti, UK mutation, B117 lentivirus, pseudovirus, pseudovirion, 78112-1, 78112-2
Shipping Temp -80C
Supplier Name BPS