Spike (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)
Product Code
78637-2
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The Spike (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) was produced with SARS-CoV-2 Spike corresponding to the initial strain (Genbank Accession #QHD43416.1) as the envelope glycoprotein instead of VSV-G. The pseudovirions contain the firefly luciferase gene; therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) can be used to measure the activity of a neutralizing antibody against SARS-CoV-2 in a Biosafety Level 2 facility.The Spike (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter) has been validated for use with target cells Vero-E6, Calu-3, and ACE2-HEK293 (BPS Bioscience #79951). Spike VSV Delta G are preferred for use in cells such as Vero-E6 and Calu-3.The infectivity of VSV-Delta G pseudotypes is restricted to a single round of replication, therefore the pseudotypes can be handled using BSL-2 containment practices.
| SKU | 78637-2 |
|---|---|
| Size | 500 µl x 2 |
| Application | Screen or titrate neutralizing antibodies against SARS-CoV-2 Spike proteinModel virus entry in Vero-E6, Calu-3, and ACE2-HEK293 cells |
| Storage | The VSV Delta G pseudovirus is shipped with dry ice. For long-term storage, it is recommended to store the virus at -80C. |
| Species | SARS-CoV-2 |
| Shipping Temp | -80C |
| Supplier Name | BPS |