Spike (B.1.429 Variant) Pseudotyped Lentivirus (Luc Reporter)

Product Code
78172-1
$975.00
Order Support
Shipping Information
Product Updates
  • Keep up to date with product offers, resources and news

  • Sign up

The Spike (B.1.429 Variant) (SARS-CoV-2) Pseudotyped Lentiviruses were produced with SARS-CoV-2 B.1.429 Variant Spike (Genbank Accession #QHD43416.1 with B.1.429 variant mutations; see below for details) as the envelope glycoproteins instead of the commonly used VSV-G. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter (Figure 1), therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (B.1.429 Variant) (SARS-CoV-2) pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 B.1.429 variant in a Biosafety Level 2 facility.Spike Mutations in B.1.429 Variant:
S13I
W152C
L452R
D614GFigureFigure 1. Schematic of the Luciferase Reporter in SARS-CoV-2 Spike Pseudovirion
More Information
SKU 78172-1
Size 100 ul
Storage Lentiviruses are shipped with dry ice. For long term storage, it is recommended to store the virus at -80C.
Gene synonyms coronavirus, covid, covid-19, covid19, Sars-cov-2 Cal20c, California variant, sars cov 2, sarscov2, CA variant, B1429 lenti, Cal.20c mutation, California lentivirus, pseudovirus, pseudovirion, Luc reporter, 78172-1, 78172-2
Shipping Temp -80C
Supplier Name BPS