NF- ?B Reporter (Luc) - Raw 264.7 Cell line
Product Code
79978
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The NF-kappaB reporter (Luc)-Raw 264.7 cell line is designed for monitoring nuclear factor Kappa B (NF-kappaB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-kappaB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-kappaB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.
| SKU | 79978 |
|---|---|
| Size | 2 vials |
| Application | Screen for activators or inhibitors of NF-kappaB signaling pathway. Screen for activators or inhibitors of RANKL/RANK pathway. |
| Storage | Store in liquid nitrogen immediately upon receipt. |
| Gene synonyms | NF-kB reporter, NFkappaB reporter, luciferase reporter, NF-kB reporter, NFkB reporter, nfkb 264.7, 264.7 raw, NF-kB, nfkb, nf-kb |
| Shipping Temp | -80C |
| Supplier Name | BPS |