NF-?B reporter (Luc) - HEK293 Cell line

Product Code
AMS.60650
$1,595.00
Order Support
Shipping Information
Product Updates
  • Keep up to date with product offers, resources and news

  • Sign up

The NF-?B reporter (Luc) HEK293 cell line is designed to monitor nuclear factor Kappa B (NF-?B) activity. It contains a firefly luciferase gene driven by four copies of the NF-?B response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or agonists of lymphokine receptors, endogenous NF-?B transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. The cell line has been functionally validated in response to human TNF-?, IL-1?, and IL-17.
More Information
SKU AMS.60650
Size 2 vials
Application The NF-?B reporter cell line is designed for screening inhibitors of NF-?B and for monitoring NF-?B signaling pathway activity.
Storage Store in liquid nitrogen immediately upon receipt.
Species Human
Cell Line HEK293
Tissue Type Kidney
Gene synonyms NF-kappaB cell line, NFkappaB cell line, luciferase reporter, NF-kappaB cell line, NFkB cell line
Shipping Temp -80C
Supplier Name BPS