Mouse Fc gamma RIV / CD16-2 Protein, His Tag
Product Code
AMS.FC4-M52H3-50ug
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FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions
| SKU | AMS.FC4-M52H3-50ug |
|---|---|
| Size | 50 ug |
| Species | Mouse |
| Expression Host | HEK293 |
| Gene symbol | Fc gamma RIV / CD16-2 |
| Tag | His |
| Accession No | NP_653142.2 |
| Gene synonyms | Fc gamma RIV,CD16-2,Fcgr4 |
| Format | Powder |
| Storage | -20C |
| Shipping Temp | Powder,RT |