Mouse Fc gamma RIV / CD16-2 Protein, His Tag

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AMS.FC4-M52H3-50ug
$300.00
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FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions
More Information
SKU AMS.FC4-M52H3-50ug
Size 50 ug
Species Mouse
Expression Host HEK293
Gene symbol Fc gamma RIV / CD16-2
Tag His
Accession No NP_653142.2
Gene synonyms Fc gamma RIV,CD16-2,Fcgr4
Format Powder
Storage -20C
Shipping Temp Powder,RT