Mouse Fc gamma RIIB / CD32b Protein, His Tag (SPR & BLI verified)

Name: Mouse Fc gamma RIIB / CD32b Protein, His Tag (SPR & BLI verified)
Brand: AMS.CDB-M52H7-50ug
SKU: AMS.CDB-M52H7-50ug
Price: 275 USD
Availability: InStock

Product Code

AMS.CDB-M52H7-50ug

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$275.00

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Overview

Receptors for the Fc region of IgG (Fc gamma R) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Three classes of human Fc gamma Rs: RI (CD64), RII (CD32), and RIII (CD16), which generate multiple isoforms, are recognized. ; There are three genes for human Fcgamma RII /CD32 (A, B, and C) and one for mouse Fcgamma RII B (CD32B). CD32 is a low affinity receptor for IgG. Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B) is also known as CD32b, FCG2, IGFR2. CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target for monoclonal antibody therapy for malignancies.

Product Specifications

More Information
SKU	AMS.CDB-M52H7-50ug
Size	50 ug
Species	Mouse
Expression Host	HEK293
Gene symbol	Fc gamma RIIB / CD32b
Tag	His
Accession No	NP_001070657
Gene synonyms	FCGR2B,CD32b,CD32,FCG2,IGFR2,CDw32
Format	Powder
Storage	-20C
Shipping Temp	Powder,RT

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Mouse Fc gamma RIIB / CD32b Protein, His Tag (SPR & BLI verified)

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