KIR3DL3/IL-2 Luciferase Reporter Jurkat Cell Line
Product Code
AMS.78322
$12,665.00
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Recombinant Jurkat cell line expressing firefly luciferase under the control of an IL-2-responsive promoter, and with constitutive expression of human KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains and Long Cytoplasmic Tail 3; GenBank accession #BC143802.1 corresponding to KIR3DL3*00402 allele). HHLA2 (B7-H7) mediates an immune-stimulatory signal via TMIGD2 (Transmembrane and immunoglobulin domain containing 2; CD28H) in naïve T cells while it delivers an immune-inhibitory signal through KIR3DL3 in activated T cells and Natural Killer (NK) cells.
| SKU | AMS.78322 |
|---|---|
| Size | 2 vials |
| Application | • Characterize the biological activity of KIR3DL3 interaction with B7-H7 • Screen for anti-B7-H7 antibodies in co-culture with B7-H7-expressing cells |
| Storage | Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80C freezer for long term storage. |
| Species | Human |
| Shipping Temp | -80C |
| Supplier Name | BPS |