Human Siglec-3 / CD33 (18-132) Protein, Fc Tag

Name: Human Siglec-3 / CD33 (18-132) Protein, Fc Tag
Brand: AMS.CD3-H5255-1mg
SKU: AMS.CD3-H5255-1mg
Price: 2890 USD
Availability: InStock

Product Code

AMS.CD3-H5255-1mg

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$2,890.00

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Overview

Myeloidcellsurfaceantigen CD33 is also known as SIGLEC3, Siglecs(sialicacidbindingIglikelectins) andGP67, is a single-pass type I membrane protein which belongs to theimmunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Human CD33 / Siglec-3 cDNA encodes a 364 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N-terminal Ig-like V-type domain, one Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail. CD33 / Siglec-3 usually considered myeloid-specific, but it can also be found on some lymphoid cells. In the immune response, CD33 / Siglec-3 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 / Siglec-3 induces apoptosis in acute myeloid leukemia.

Product Specifications

More Information
SKU	AMS.CD3-H5255-1mg
Size	1 mg
Species	Human
Expression Host	HEK293
Gene symbol	siglec-3
Tag	FC
Accession No	NP_001076087.1
Gene synonyms	CD33,SIGLEC3,gp67
Format	Powder
Storage	-20C
Shipping Temp	Powder,RT

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We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells.

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The CELLBANKER® series of cryopreservation media allows for the stable long-term storage of any cell type, including sensitive cell lines.

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AMSBIO offers one of the largest selection of active recombinant enzymes and enzyme activity assays for profiling, inhibitor screening assays, and drug discovery.

AMSBIO offers one of the largest selection of active recombinant enzymes and enzyme activity assays for profiling, inhibitor screening assays, and drug discovery.

AMSBIO offers one of the largest selection of active recombinant enzymes and enzyme activity assays for profiling, inhibitor screening assays, and drug discovery.

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We supply a range of superior magnetic products each uniquely suited to specific protein purification, proteomics and genomics applications.

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Human Siglec-3 / CD33 (18-132) Protein, Fc Tag

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