Human Nectin-4 Protein, Fc Tag
Product Code
AMS.NE4-H5255-1mg
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Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.
| SKU | AMS.NE4-H5255-1mg |
|---|---|
| Size | 1 mg |
| Species | Human |
| Expression Host | HEK293 |
| Tag | FC |
| Accession No | NP_112178.2 |
| Gene synonyms | Nectin-4 |
| Format | Powder |
| Storage | -20C |
| Shipping Temp | Powder,RT |