Human Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, Tag Free&Tag Free
Product Code
AMS.IT1-H5213-1mg
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Integrin alpha-5/beta-1 is a receptor for ibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-V/beta-1 is also a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition.
| SKU | AMS.IT1-H5213-1mg |
|---|---|
| Size | 1 mg |
| Species | Human |
| Expression Host | HEK293 |
| Gene symbol | Integrin alpha V beta 1 |
| Tag | Untagged |
| Accession No | NP_002201.1, NP_002202.2 |
| Gene synonyms | Integrin alpha V beta 1,ITGAV&ITGB1 |
| Format | Powder |
| Storage | -20C |
| Shipping Temp | Powder,RT |