Human Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, Tag Free&Tag Free

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AMS.IT1-H5213-1mg
$3,600.00
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Integrin alpha-5/beta-1 is a receptor for ibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-V/beta-1 is also a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition.
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SKU AMS.IT1-H5213-1mg
Size 1 mg
Species Human
Expression Host HEK293
Gene symbol Integrin alpha V beta 1
Tag Untagged
Accession No NP_002201.1, NP_002202.2
Gene synonyms Integrin alpha V beta 1,ITGAV&ITGB1
Format Powder
Storage -20C
Shipping Temp Powder,RT