Human Fc gamma RIIIB / CD16b (NA1) Protein, His Tag (SPR& BLI verified)

Name: Human Fc gamma RIIIB / CD16b (NA1) Protein, His Tag (SPR& BLI verified)
Brand: AMS.CDB-H5227-50ug
SKU: AMS.CDB-H5227-50ug
Price: 275 USD
Availability: InStock

Product Code

AMS.CDB-H5227-50ug

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$275.00

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Overview

CD16 is a low affinity Fc receptor, and has been identified as Fc receptors FcgammaRIIIa (CD16a) and FcgammaRIIIb (CD16b). These receptors bind to the Fc portion of IgG antibodies. CD16 encoded by two different highly homologous genes in a cell type-specific manner.CD16 is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages.; CD16B is also kown as FCGR3B and FCG3B, is expressed specifically by polymorphonuclear leukocytes (neutrophils) and stimulated eosinophils. CD16B is the low affinity receptor for the Fc region of immunoglobulins gamma. FCGR3B binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, FCG3B is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. CD16B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

Product Specifications

More Information
SKU	AMS.CDB-H5227-50ug
Size	50 ug
Species	Human
Expression Host	HEK293
Gene symbol	Fc gamma RIIIB / CD16b (NA1)
Tag	His
Accession No	AAA35881.1
Gene synonyms	Fc gamma RIIIB / CD16b (NA1),FCGR3B,CD16B,FCG3B,FCGR3,FCG3,IGFR3
Format	Powder
Storage	-20C
Shipping Temp	Powder,RT

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Human Fc gamma RIIIB / CD16b (NA1) Protein, His Tag (SPR& BLI verified)

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