Human Activin RIB / ACVR1B Protein, His Tag
Product Code
AMS.ACB-H52H4-1mg
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Activin receptor type-1B (ACVR1B) is also known as Activin receptor-like kinase 4 (ALK-4), Serine/threonine-protein kinase receptor R2 (SKR2), which belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. ACVR1B contains one GS domain and one protein kinase domain. The catalytic activity of ACVR1B is “ATP + [receptor-protein] = ADP + [receptor-protein] phosphateâ€_x009d_. ACVR1B acts as a transducer of activin or activin like ligands (e.g., inhibin) signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B. These go on to recruit the R-SMADs SMAD2 or SMAD3. ACVR1B also transduces signals of nodal, GDF-1, and Vg1.
| SKU | AMS.ACB-H52H4-1mg |
|---|---|
| Size | 1 mg |
| Species | Human |
| Expression Host | HEK293 |
| Gene symbol | Activin RIB |
| Tag | His |
| Accession No | AAH00254 |
| Gene synonyms | ACVR1b,ALK4,ACVRLK4,ACTR-IB,SKR2 |
| Format | Powder |
| Storage | -20C |
| Shipping Temp | Powder,RT |