CD40/NF-?B Reporter (Luc) - HEK293 Stable Cell Line
Product Code
AMS.60626
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Recombinant HEK293 cell line expressing full length human CD40 (Tumor necrosis factor receptor superfamily member 5; TNFRSF5). Expression is confirmed by real-time qPCR and Western Blot. This NF-?B luciferase reporter construct is stably integrated into the genome. The firefly luciferase gene is controlled by 4 copies of NF-?B response element located upstream of the TATA promoter. Following activation by human CD40 ligand, NF-?B transcription factor binds to the DNA response elements to induce transcription of the luciferase gene.
| SKU | AMS.60626 |
|---|---|
| Size | 2 vials |
| Application | The CD40 NF-?B Reporter HEK293 Stable Cell Line is ideal for High Throughput Screening (HTS) to identify potential CD40 agonistic monoclonal antibodies and CD40-specific inhibitors. |
| Storage | Immediately upon receipt, store vials in liquid nitrogen. |
| Species | Human |
| Cell Line | HEK293 |
| Tissue Type | Kidney |
| Gene synonyms | CD40 cell line, luciferase reporter, CD40 NF-kB cell line, NFkB cell line |
| Shipping Temp | Dry Ice |
| Supplier Name | BPS |