Cas9-Expressing MDA-MB-231 cell pool
Product Code
78069
Order Support
- Email: [email protected]
Order Support
- Email: [email protected]
Order Support
-
T: +1 (800) 987 0985 (toll free)
-
Email: [email protected]
Order Support
-
Email: [email protected]
Shipping Information
-
Delivery charges will be calculated during checkout
Product Updates
-
Keep up to date with product offers, resources and news
Cas9 (Streptococcus pyogenes CRISPR associated protein 9) is an endonuclease enzyme that, when recruited to a specific DNA sequence by the sgRNA (single guide RNA), introduces a double stranded break into the DNA. This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the targeted gene. Cas9-expressing MDA-MB-231 cells can be transduced or electroporated with sgRNA targeting a gene of interest to quickly generate knock-out cell pools or cell lines.
| SKU | 78069 |
|---|---|
| Size | 2 million cells |
| Application | 1. Quickly generating knock-out cell pools or cell lines in MDA-MB-231 cells. 2. Implementing sgRNA screens in Cas9-expressing MDA-MB-231 cells. |
| Storage | Immediately upon receipt, store in liquid nitrogen. |
| Gene synonyms | SpCas9 cell pool, CRISPR cell pool, Cas9 cell pool, MDA-MB-231 cells, Human metastatic mammary adenocarcinoma cells |
| Shipping Temp | -80C |
| Supplier Name | BPS |