Anti-Mesothelin CAR Lentivirus (P4 ScFv-CD8-4-1BB-CD3?)
Product Code
AMS.78703
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The Anti-mesothelin CAR lentiviruses are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce the ScFv (single-chain fragment variable) of anti-mesothelin (Clone P4) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3? signaling domains (Figure 1).A
B
Figure 1. (A) Schematic of the lenti-vector used to generate the anti-mesothelin CAR lentivirus and (B) Construct diagram showing components of the anti-mesothelin CAR.
| SKU | AMS.78703 |
|---|---|
| Size | 50 ul |
| Storage | Lentiviruses are shipped with dry ice. For long term storage, it is recommended to store the virus at -80C. |
| Gene synonyms | CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, Megakaryocyte-potentiating factor (MPF), MSLN, MPF |
| Shipping Temp | -80C |
| Supplier Name | BPS |