Anti-CD22 CAR Lentivirus (Clone m971 ScFv-CD8-4-1BB-CD3?)
Product Code
AMS.78608
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The anti-CD22 CAR lentiviruses are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce the ScFv (single-chain variable fragment) of anti-CD22 (clone m971) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3? signaling domains (below).
Schematic of the lenti-vector used to generate the anti-CD22 CAR lentivirus
Construct diagram showing components of the anti-CD22 CAR
| SKU | AMS.78608 |
|---|---|
| Size | 50 ul |
| Application | Ideal as a positive control for anti-CD22 CAR evaluation in T cells; useful for transduction optimization. |
| Storage | Lentiviruses are shipped with dry ice. For long term storage, it is recommended to store the virus at -80C. |
| Shipping Temp | -80C |
| Supplier Name | BPS |