Anti-CD19 CAR-T Cells
Product Code
AMS.78171-2
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The anti-CD19 CAR-T cells are produced by high-titer lentiviral transduction of human primary CD4+CD8+ T cells using the anti-CD19 CAR Lentivirus (CD19 ScFv-CD8-4-1BB-CD3?; SIN Vector). These ready-to use CAR-T cells express an anti-CD19 CAR consisting the ScFv of CD19 (clone FMC63) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3? signaling domains.These CAR-T cells have been validated using flow cytometry (to determine the CAR expression) and co-culture cytotoxicity assays.
| SKU | AMS.78171-2 |
|---|---|
| Size | 5 vials |
| Application | Positive control for anti-CD19 CAR-T cellsScreening inhibitors or activators of anti-CD19 CAR-T cytotoxicityDesign and optimize co-culture cytotoxicity assay |
| Storage | Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80C freezer for long term storage. |
| Shipping Temp | -80C |
| Supplier Name | BPS |