Anti-CD19 CAR negative control/ NFAT (Luciferase) Reporter Jurkat Cell Line (CD19 SCFV-CD28 transmembrane motif)
Product Code
79854
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Anti-CD19 CAR negative control/NFAT-luciferase reporter Jurkat cell line is a double stable cell line expressing anti-CD19 CAR negative control and NFAT-luciferase reporter. The anti-CD19 CAR negative control consists of anti-CD19 scFv linked to the CD28 transmembrane motif without any intracellular signaling domains. The reporter cell line has been validated for anti- CD19 expression by FACS, while the stimulation by target cells including CD19/CHO recombinant cell line has not activated the luciferase reporter gene in this cell line. The cell line can be used for the negative control of anti-CD19 CAR/Jurkat-NFAT cell line (BPS Bioscience, #79853).
| SKU | 79854 |
|---|---|
| Size | 2 vials |
| Application | Validate different CAR designs and constructs for their specificity, efficacy and potency before proceeding into patient-derived primary T cells. Intracellular co-stimulatory and activation domain comparison. |
| Storage | Immediately upon receipt, store in liquid nitrogen. |
| Shipping Temp | -80C |
| Supplier Name | BPS |